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Job summary

Main area
Toxicology
Grade
Civil Service: Senior Executive Officer (SEO)
Contract
Permanent
Hours
  • Full time
  • Part time
  • Job share
  • Flexible working
37.5 hours per week
Job ref
919-JI-302675-EXT
Employer
UK Health Security Agency
Employer type
Public (Non NHS)
Site
Scientific Campus
Town
Chilton, Oxfordshire
Salary
£44,148 - £50,121 Per Annum, Pro Rata
Salary period
Yearly
Closing
05/08/2026 23:59

Employer heading

UK Health Security Agency logo

Senior Toxicologist

Civil Service: Senior Executive Officer (SEO)

The UK Health Security Agency (UKHSA) prevents, prepares for and responds to infectious diseases, and environmental hazards, to keep all our communities safe, save lives and protect livelihoods.

We provide scientific and operational leadership, working with local, national and international partners to protect the public’s health and build the nation’s health security capability.

UKHSA is an executive agency, sponsored by the Department of Health and Social Care.

Job overview

The Radiation, Chemical, Climate and Environmental Hazards Directorate (RCCE) at the UK Health Security Agency provides evidence and advice to protect health from Radiation, Chemical and Environmental Hazards. The Toxicology Department provides Public Health advice to other parts of RCCE, the Department of Health and Social Care and other government departments and agencies, Local Authorities and other stakeholders including members of the public on the risks to health from environmental hazards (chemicals, particles and bioaerosols). The Toxicology Department undertakes research that underpins chemical regulation and policy development. All of the research underpins the UKHSA role in public health protection from environmental hazards.

The International Regulation Group within the Toxicology Department undertakes translational research activities using in silico, in vitro and in vivo models for chemical hazard assessment, and works to harmonise these tools in collaboration with international partners, particularly the Organisation for Economic Co-operation and Development’s (OECD) Test Guideline Programme and related bodies. The OECD Environment Health and Safety programme covers the safe use of chemicals, nanomaterials, pesticides, biocides, and products of modern biotechnology. It aims to protect health and the environment, while avoiding duplication of effort, ensuring that efficiencies are made and barriers to trade avoided.

Main duties of the job

  • The post is a predominantly desk based scientific research role. You may manage junior toxicologists.
  • The post holder will provide and contribute to the toxicology and public health input to international chemical regulation programmes specifically, but not exclusively the OECD Test Guidelines programme and related OECD work.
  • This will involve collaborating and coordinating with leading senior scientists in UKHSA and across UK government and associated agencies and to ensure the standard of oversight and UK contributions to the Test Guideline and other regulatory programmes is maintained and developed. This will require the ability critically review complex data sets and carry out critical reviews of evidence. Experience in computational tool development and modelling of data, or laboratory skills, is highly desirable. The post holder will support the UK Human Health National Coordinator for the OECD Test Guideline programme, and the Working Party on Hazard Assessment as required and will publish research findings in leading journals in both a lead and senior author capacity and make presentations at learned societies and the OECD. They will be expected to apply for external funding to support translational research activities.
  • The postholder will also be expected to input into a programme of laboratory development and validation of New Approach Methodologies, including in silico tools, in the chemicals regulatory space addressing Refinement and Replacement.

Continues below

Working for our organisation

We pride ourselves as being an employer of choice, where Everyone Matters promoting equality of opportunity to actively encourage applications from everyone, including groups currently underrepresented in our workforce.   

UKHSA ethos is to be an inclusive organisation for all our staff and stakeholders. To create, nurture and sustain an inclusive culture, where differences drive innovative solutions to meet the needs of our workforce and wider communities. We do this through celebrating and protecting differences by removing barriers and promoting equity and equality of opportunity for all.  

Please visit our careers site for more information https://gov.uk/ukhsa/careers

Detailed job description and main responsibilities

·       Contribute to and take responsibility for specific aspects of the design, development and completion of in vivo and in vitro data analysis tasks.

·       Develop expert scientific and regulatory relevant advice on the hazard assessment of chemicals.

·       Design, execute and undertake studies to support the development and validation of appropriate methods for chemical testing to support regulatory objectives for chemical safety.

·       Contribute to the management of regulatory /translational research projects including: planning, experimental design, procedures and data analysis.

·       Be the support lead for UKHSA, collaborating with senior government officials and officials in national and international bodies in particular the OECD, in the analysis and interpretation of complex scientific data in a specific area and in the provision of advice.

·       Collaborate with internal and external scientists in the development of proposals for funding and the development of programmes for experimental work.

·       Produce sound scientific papers for external peer reviewed publication and give presentations at levels including international conferences.

·       Assist in the supervision of junior staff, internal and from collaborating organisations (eg MSc, PhD students).

·       Undertake specific development tasks for the Group Leader (eg Health and Safety responsibilities).

 

This list is not exhaustive

 

Essential criteria

  • PhD qualification (or equivalent) relevant to the field of toxicology and/or experience of working at a similar level in a relevant area of regulatory toxicology
  • Experience of assessing health risks from chemicals
  • Awareness of broad public health and environmental issues
  • Ability to critically assess relevant data and information to assess the toxicity of chemicals journals
  • Experience in vitro cell culture and /or in silico tool development
  • Good scientific writing skills
  • Good communication and interpersonal skills.
  • Ability to meet deadlines, and plan work over short-, medium- and long-term timeframes
  • An understanding of and commitment to equality of opportunity and good working relationships.

Desirable criteria:

  • Inclusion in UK Register of Toxicologists
  • Experience in test method (pre)validation
  • Experience in public health
  • Regulatory experience
  • Experience in industry
  • Experience of teaching or training

Selection Process Details(Competency based) 

This vacancy will be assessed using a competency-based framework which will assess your qualifications,knowledgeand experience and / or skills and abilities outlined in the essential criteria. 

Stage 1: Application & Sift 

Competency Based 

You willbe requiredto complete an application form. You will be assessed on the listed9essential criteria, and this will be in the form of a: 

  • Application form (Employer/ Activity history’ section on the application) 
  • 1500 word supporting statement.   

This should outline how you consider your skills, experienceand knowledge provide evidence of your suitability for the role, with reference to the essential criteria.   
 
You will receive a joint score for your application form and statement. (The application form is the kind of information you would put into your C.V –please beadvisedyou will not be able to upload your CV. Please complete the application form in as much detail as possible). Please do not email us your CV.

HealthjobsUK has a word limit of 1500. 

Longlisting: 
 
In the event ofa large number ofapplications,we will longlist into 3 piles of: 

  • Meets all essential criteria   
  • Meets some essential criteria   
  • Meets no essential criteria   

If used, the pile(s) that meets ALL essential criteria’ willproceedto shortlisting.   

Shortlisting: 
 
In the event ofa large number ofapplications we will conductan initialsift, on the lead criteria of: 

  • PhD qualification (or equivalent) relevant to the field of toxicology and/or experience of working at a similar level in a relevant area of regulatory toxicology
  • Experience in vitro cell culture and /or in silico tool development
  • Good scientific writing skills

Desirable criteria may be usedin the event ofa large number ofapplications/largeamountof successful candidates.

If you are successful at this stage, you will progress to interview & assessment.  

Feedback will not be provided at this stage. 

Stage 2: Interview 

Competency Based 

You will be invited to a single face to faceinterview at our Scientific Campus in Chilton

When face to face interviewsareplanned, in exceptional circumstances, we may be able to offer a remote interview. 

Knowledge, experience, skills & abilities will be tested at interview in the form of questions.

There will be a Presentation.

The subject of this will be - How your work experience can contribute to the needs of the role. This should last no longer than 10 minutes, with 5 minutes of questions afterwards.

Interviews dates to be confirmed.  

Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records. 

Eligibility Criteria

 

External: Open to all external applicants (anyone) from outside the Civil

Service (including internal applicants). 

 

Location

This role is being offered as hybrid working based at our Scientific Campus in Chilton. We offer great flexible working opportunities at UKHSA and operate using a hybrid working model where business needs allow. This provides us with greater flexibility about how and where we work, to get the best from our workforce. As a hybrid worker, you will be expected to spend a minimum of 60% of your contractual working hours (approximately 3 days a week pro rata, (averaged over a month) working at our campus.

Security Clearance Level Requirement

Successful candidates must pass a basic disclosure and barring security check before they can be appointed.

Successful candidates must meet the security requirements before they can be appointed. The level of security needed is Counter-Terrorist Check

When based at our scientific campus, you will be required to have a minimum of a Counter Terrorism Check security vetting check as a minimum. For meaningful National Security Vetting checks to be carried out individuals need to have lived in the UK for a sufficient period of time. You should normally have been resident in the United Kingdom for the last 3 years as the role requires Counter Terrorism Check (CTC) clearance. In exceptional circumstances UK residency less than the outlined periods may not necessarily bar you from gaining national security vetting and applicants should contact the Vacancy Holder/Recruiting Manager listed in the advert for further advice.

Salary Information

If you are successful at interview, and are moving from another government department, NHS, or Local Authority, the relevant starting salary principles for level transfers or promotions will apply. Otherwise, roles are offered at the pay scale minimum for the grade, but in exceptional circumstances there may be flexibility if you are able to demonstrate you are already in receipt of an existing, higher salary. Pay increases are through the relevant annual pay award for the role and terms. Please be aware that the salary is based on the office location.

 

 

 

Person specification

Application form & supporting statement

Essential criteria
  • Application form & supporting statement

Interview - Questions

Essential criteria
  • Questions on knowledge, experience, skills & abilities

Interview - Presentation

Essential criteria
  • Presentation

Employer certification / accreditation badges

Purple SpaceApprenticeships logoNo smoking policyAge positiveImproving working livesMindful employer.  Being positive about mental health.Disability confident employerThe Employers Network for Equality & Inclusion (enei) is the UK's leading employer network covering all aspects of equality and inclusion issues in the workplace.Carer Confident -AccomplishedHappy to Talk Flexible Working

Documents to download

Apply online now

Further details / informal visits contact

Name
John Inglis
Job title
Resourcing Officer
Email address
[email protected]
Additional information

If you need any questions answered relating to the position, you can also email [email protected] 

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