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Job summary

Main area
Science and Engineering
Grade
Civil Service: Executive Officer (EO)
Contract
Permanent
Hours
  • Full time
  • Part time
  • Job share
  • Flexible working
37.5 hours per week
Job ref
919-CA-301931-EXT
Employer
UK Health Security Agency
Employer type
Public (Non NHS)
Site
Scientific Campus / Lab : Porton
Town
Porton
Salary
£28,547 - £33,196 pro rata per annum
Salary period
Yearly
Closing
25/06/2026 23:59

Employer heading

UK Health Security Agency logo

Scientist

Civil Service: Executive Officer (EO)

The UK Health Security Agency (UKHSA) prevents, prepares for and responds to infectious diseases, and environmental hazards, to keep all our communities safe, save lives and protect livelihoods.

We provide scientific and operational leadership, working with local, national and international partners to protect the public’s health and build the nation’s health security capability.

UKHSA is an executive agency, sponsored by the Department of Health and Social Care.

Job overview

UKHSA-Porton plays an important role in preparing for and coordinating responses to potential healthcare emergencies, including possible acts of deliberate release and undertakes both basic and applied research into understanding infectious diseases.

The Vaccine Development & Evaluation Centre at Porton has approximately 250 staff, performing a range of research activities, including high containment level work. The department’s work covers a broad range of projects involving the development and evaluation of interventions into a range of infectious diseases e.g., tuberculosis (TB), meningitis, anthrax and SARS-CoV2.

The Advanced Cellular Immunology Group (ACI) use pre-clinical non-human primate (NHP) models to assess the safety, efficacy, and immunogenicity of arrange of novel vaccines and therapeutics to protect against threats and treat viral and bacterial respiratory pathogens such as SARS-CoV2, Influenza and Tuberculosis, a disease which was responsible for ~1.2 million deaths in 2024.

You will be involved in the processing of blood samples and application of immunoassays to measure the mycobacteria-specific cellular immune response at ACDP Containment Levels 2 & 3 using a range of techniques including the ELISPOT assay and flow cytometry.

Main duties of the job

  • Implement and utilise a range of methods, assays, and techniques (including PBMC isolation, ELISPOT) at ACDP containment levels 2 & 3 in support of all activities associated with the group’s projects and to ensure project targets are met.
  • Training will be provided on assays and techniques required for the post.
  • Take responsibility for the provision of reagents and consumables required for project area.
  • Assist the project team to identify, evaluate and adapt new technologies where appropriate and to ensure that the project operates to a high scientific standard using current methods.
  • Provide reports through analysis of data using software and databases as necessary, to meet project targets and for preparation of presentations and publications.
  • To perform any other duties required by the line manager commensurate with grade.
  • To ensure that the project team undertakes work in accordance with UKHSA’s Code of Safety Practice and to work within any Quality Systems that are applicable to the site.
  • To comply with all UKHSA policies and procedures.

Other

  • The above is only an outline of the tasks, responsibilities and outcomes required of the role. You will carry out any other duties as may reasonably be
    required by the directorate.
  • The job description and person specification may be reviewed on an ongoing basis in accordance with the changing needs of the organization

Working for our organisation

We pride ourselves as being an employer of choice, where Everyone Matters promoting equality of opportunity to actively encourage applications from everyone, including groups currently underrepresented in our workforce.   

UKHSA ethos is to be an inclusive organisation for all our staff and stakeholders. To create, nurture and sustain an inclusive culture, where differences drive innovative solutions to meet the needs of our workforce and wider communities. We do this through celebrating and protecting differences by removing barriers and promoting equity and equality of opportunity for all.  

Please visit our careers site for more information https://gov.uk/ukhsa/careers

Detailed job description and main responsibilities

Working as a Scientist within ACI, you will support the processing of blood samples from safety, efficacy and immunogenicity studies evaluating novel tuberculosis vaccines and drug treatments in the non-human primate model.

With the support of your manager and colleagues, you will be required to carry out immunoassays to analyse mycobacteria-specific cellular immune responses at ACDP Containment Levels 2 & 3. This role offers the opportunity to learn an array of immunological techniques such as: PBMC isolation and cell culture, bacteriology, multi-parameter flow cytometry, and multiplex ELISA and ELISPOT methods.

These methods will be used to investigate potential correlates of protection and biomarkers of disease to aid in the acceleration of the development of new vaccines and treatments. You will be responsible for the provision of reagents and consumables required to carry out study work within the project area and assist in the supervision of laboratory areas associated with the team’s activities.

Our ideal candidate has a keen interest in immunological research and is motivated to deliver results. They are comfortable working under pressure as well as to strict timelines and will ensure projects operate to the highest scientific standards.

Essential role criteria 

  • Education to BSc level in an biological science subject ( e.g. Biology, Immunology, Microbiology etc... ) or equivalent experience working in a laboratory. 
  • Experience in relevant methods such as preclinical models, cellular immunoassays, flow cytometry and high containment working practices acquired through previous employment, placements, or taught course

Desirable role criteria: 

  • Experience of having worked within a regulated environment. (e.g. ISO9001). 
  • Experience of working with in vivo models of M. tuberculosis. 
  • Background knowledge of M.tb infection, immunology, vaccines and therapeutics 
  • Experience of complex data analysis, presentations, reports & publication. 
  • Good communication skills. Able to work flexibly to meet deadlines. Ability to work in teams and independently. Self-motivating, organised, and meticulous.
  • Willing to undertake further training. 
  • Experience in scientific writing e.g. creating reports, and publications. Experience of creating and giving presentations.  
  • An understanding of and commitment to equality of opportunity and good working relationships.

Selection Process Details

This vacancy is using Success Profiles and will assess your Behaviours/ Experience/Technical skills.

Stage 1: Application & Sift   Success Profiles - GOV.UK 

You will be required to complete an application form. You will be assessed on the listed  essential criteria, and this will be in the form of a:  

  • Application form (Employer/ Activity history’ section on the application) 

  • 1, 000 word Supporting Statement

Healthjobs UK has a word limit of 1, 500 your supporting statement must be no more than the limit. We will not consider any words over the limit.  

This should outline how you consider your skills, experience and knowledge provide evidence of your suitability for the role, with reference to the essential criteria.

You will receive a joint score for your application form and statement. (The application form is the kind of information you would put into your CV . Please be advised you will not be able to upload your CV. Please complete the application form in as much detail as possible). Please do not email us your CV.

Longlisting

In the event of a large number of applications we will longlist into 3 piles of: 

  • Meets all essential criteria  
  • Meets some essential criteria  
  • Meets no essential criteria  

If used, the pile(s) ‘Meets all essential criteria‘ will proceed to shortlisting.

Shortlisting

In the event of a large number of applications we may conduct an initial sift, on the lead criteria of :

  • Education to BSc level in an biological science subject ( e.g. Biology, Immunology, Microbiology etc... ) or equivalent experience working in a laboratory.
  • Experience in relevant methods acquired through previous employment, placements, or taught course.

Desirable criteria will be used in the event of a large number of applications/successful candidates. 

If you are successful at this stage, you will progress to interview.

Feedback will not be provided at this stage. 

Stage 2: Interview Success Profiles - GOV.UK 

You will be invited to a (single) remote interview. 

Behaviours,  Experience, Technical skills will be tested at interview.

The Behaviours tested during the interview stage will be :

  • Delivering at Pace
  • Working Together

Interviews dates to be confirmed. 

Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.

Eligibility Criteria - External

Open to all external applicants (anyone) from outside the Civil Service (including internal applicants).  

Location 

This role is being offered as office/lab based at our Scientific Campus in Porton (Salisbury). 

If based at one of our scientific campuses, you will be required to have a Counter Terrorism Check security vetting check as a minimum. For meaningful National Security Vetting checks to be carried out individuals need to have lived in the UK for a sufficient period of time. You should normally have been resident in the United Kingdom for the last 3 years as the role requires Counter Terrorism Check (CTC) clearance. In exceptional circumstances UK residency less than the outlined periods may not necessarily bar you from gaining national security vetting and applicants should contact the Vacancy Holder/Recruiting Manager listed in the advert for further advice.

Security Clearance Level Requirement  

Successful candidates must pass a Basic Disclosure and Barring Security (DBS) check.   

Successful candidates must meet the security requirements before they can be appointed. The level of security needed is:

  • Basic Personnel Security Standard 
  • Counter-terrorist Check

Salary Information 

If you are successful at interview, and are moving from another government department, NHS, or Local Authority, the relevant starting salary principles for level transfers or promotions will apply. Otherwise, roles are offered at the pay scale minimum for the grade, but in exceptional circumstances there may be flexibility if you are able to demonstrate you are already in receipt of an existing, higher salary. Pay increases are through the relevant annual pay award for the role and terms. 

 

Person specification

Application Form and Supporting Statement

Essential criteria
  • Application Form and Supporting Statement

Interview - Behaviours

Essential criteria
  • Working Together
  • Delivering at Pace

Employer certification / accreditation badges

Purple SpaceApprenticeships logoNo smoking policyAge positiveImproving working livesMindful employer.  Being positive about mental health.Disability confident employerThe Employers Network for Equality & Inclusion (enei) is the UK's leading employer network covering all aspects of equality and inclusion issues in the workplace.Carer Confident -AccomplishedHappy to Talk Flexible Working

Documents to download

Apply online now

Further details / informal visits contact

Name
Conny Agyei
Job title
Resourcing Officer
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