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Job summary

Main area
Bioinformatician
Grade
Civil Service: Higher Executive Officer (HEO)
Contract
Fixed term: 11 months (FTC till 31/03/26)
Hours
  • Full time
  • Part time
  • Job share
  • Flexible working
37.5 hours per week
Job ref
919-GB-301386-EXT
Employer
UK Health Security Agency
Employer type
Public (Non NHS)
Site
Colindale
Town
Colindale
Salary
£36,187 - £43,552 Per annum, Pro rata
Salary period
Yearly
Closing
15/05/2025 23:59

Employer heading

UK Health Security Agency logo

Bioinformatician

Civil Service: Higher Executive Officer (HEO)

The United Kingdom Health Security Agency (UKHSA) is a system leader for health security; taking action internationally to strengthen global health security, providing trusted advice to government and the public and reducing inequalities in the way different communities experience and are impacted by infectious disease, environmental hazards, and other threats to health.

UKHSA’s remit, as an agency with a global-to-local reach, is to protect the health of the nation from infectious diseases and other external threats to health. As the nation’s expert national health security agency UKHSA will:

  • Prevent: anticipate threats to health and help build the nation’s readiness, defences and health security
  • Detect: use cutting edge environmental and biological surveillance to proactively detect and monitor infectious diseases and threats to health
  • Analyse: use world-class science and data analytics to assess and continually monitor threats to health, identifying how best to control and mitigate the risks
  • Respond: take rapid, collaborative and effective actions nationally and locally to mitigate threats to health when they materialise
  • Lead: lead strong and sustainable global, national, regional and local partnerships designed to save lives, protect the nation from public health threats and reduce inequalities.

Job overview

The Gastrointestinal Bacteria Reference Unit (GBRU) undertakes surveillance, advises on outbreak investigation and on any public health risk. With the increasing development of genomics including the generation of sequence data from whole genomic sequencing, this role is key to supporting the Unit with necessary bioinformatic expertise and advice regarding appropriate analysis tools, equipment and procedures for the analysis of complex scientific information for the development and support of reference services

You will support development of bioinformatics and public health informatics for GBRU: 

  • Compile, in appropriate databases and formats, complex data arising from whole-genome sequencing (WGS) from a range of gastrointestinal bacterial pathogens.
  • Support the development bioinformatics tools and pipelines suitable for analysis and comparison of the genome sequences generated.
  • Undertake analyses on data arising from WGS for reference service delivery, including outbreak analysis, bacterial discrimination, and service development projects, and to assist in the timely generation of meaningful reports to customers.
  • Support preparation of reports, posters and publications arising from data at national and international meetings

Main duties of the job

  • Contribute to day-to-day running and maintenance of the software and computer systems delivering existing Whole Genome Sequencing (WGS) pipelines. 
  • Work with bioinformaticians at UKHSA on efficient bioinformatics pipelines suitable for analysis and comparative genomics of bacterial genome sequences, within GBRU’s remit. 
  • Compile data arising from priority projects/routine data to characterize bacterial pathogens
  • Assist to provide a flexible laboratory response to emergency public health needs including outbreaks of gastrointestinal disease and general investigations of illness as appropriate
  • Assist with evaluation and implementation of new techniques / methods to the unit that enhance effectiveness of the laboratory work with genomic platforms
  • Undertake analysis of data arising from GBRU genome sequencing projects, including temporal and geographical cluster analysis, characterization of clones, resistance / virulence array data, full genome or resistance plasmid sequencing
  • Train others in the use of tools developed
  • Write and update working instruction and SOPs
  • Prepare reports, posters and publications arising from the data analysis and present findings at internal and/or external meetings 
  • Comply with safety and quality protocols and procedures at all times.

For a full list of the main duties and responsibilities of the role, please refer to the attached Job Description. 

Working for our organisation

We pride ourselves as being an employer of choice, where Everyone Matters promoting equality of opportunity to actively encourage applications from everyone, including groups currently underrepresented in our workforce.   

UKHSA ethos is to be an inclusive organisation for all our staff and stakeholders. To create, nurture and sustain an inclusive culture, where differences drive innovative solutions to meet the needs of our workforce and wider communities. We do this through celebrating and protecting differences by removing barriers and promoting equity and equality of opportunity for all.  

Please visit our careers site for more information https://gov.uk/ukhsa/careers

Detailed job description and main responsibilities

Essential role criteria:

  • Degree in Bioinformatics or a related discipline such as Computer science, informatics or microbiology and/or relevant experience in computer science or health informatics
  • Application and adaptation of bioinformatics tools to analyse biological data using the UNIX command line
  • Experience in the analysis of large molecular datasets (incl. next-generation/ whole genome sequences)
  • Demonstrable experience in programming and script writing (eg. Python, bash) 
  • Good time management skills, the ability to multitask and be able to work to deadlines and achieve milestones.
  • An understanding of and commitment to equality of opportunity and good working relationships.

Desirable role criteria:

  • An understanding of the principals of DNA sequence analysis and phylogenetics
  • Knowledge of molecular microbiology and molecular epidemiology
  • Experience in working with complex datasets and within challenging environments
  • Knowledge of Bacterial Pathogens
  • Understanding of the public sector (working with various government bodies)
  • Database management (PostgreSQL, SQL queries)
  • Public speaking at national or international meetings
  • Problem solving skills and ability to respond to sudden unexpected demands

Selection Process Details: 

This vacancy will be assessed using a competency-based framework which will assess your qualifications, knowledge and experience and / or skills and abilities outlined in the essential criteria.  

Stage 1: Application & Sift - Competency-based assessment

You will be required to complete an application form. You will be assessed on the listed (6) essential criteria, and this will be in the form of a:  

  • Application form (‘Employer/ Activity history’ section on the application) 
  • 1250 word Statement of Suitability.  

This should outline how your skills, experience, and knowledge, provide evidence of your suitability for the role, with reference to the essential criteria.  

The Application form and Statement of Suitability will be marked together. 

Longlisting:

In the event of a large number of applications we will longlist into 3 piles of: 

  • Meets all essential criteria  
  • Meets some essential criteria  
  • Meets no essential criteria  

The following will be taken through to the next stage: 

  • Meets all essential criteria  

Shortlisting:

In the event of a large number of applications we will shortlist on the following:

  • Degree in Bioinformatics or a related discipline

Desirable criteria may be used in the event of a large number of applications / large amount of successful candidates  

If you are successful at this stage, you will progress to interview & assessment  

Please do not exceed 1250 wordsWe will not consider any words over and above this number. 

Feedback will not be provided at this stage. 

Please note you will not be able to upload your CV. You must complete the application form in as much detail as possible. Please do not email us your CV.  

Stage 2: Interview (competency based) 

You will be invited to a (single) face to face interview at Colindale. If face to face interviews are planned, in exceptional circumstances, we may be able to offer a remote interview.

Knowledge, experience, skills & abilities will be tested at interview   

There will be a 5-10 minute Presentation. Further details will be provided at this stage.

Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records. 

Eligibility Criteria - External  

Open to all external applicants (anyone) from outside the Civil Service (including by definition internal applicants).  

Location 

This role is being offered as hybrid working based at our Core HQ in Colindale. We offer great flexible working opportunities at UKHSA and operate using a hybrid working model where business needs allow. This provides us with greater flexibility about how and where we work, to get the best from our workforce. As a hybrid worker, you will be expected to spend a minimum of 60% of your contractual working hours (approximately 3 days a week pro rata, (averaged over a month). Our core HQ offices are modern and newly refurbished with excellent city centre transport link and benefit from benefit from co-location with other government departments such as the Department for Health and Social Care (DHSC).

Security Clearance Level Requirement 

Successful candidates must pass a disclosure and barring security check.   

Successful candidates must meet the security requirements before they can be appointed. The level of security needed is Counter-terrorist Check.

For meaningful National Security Vetting checks to be carried out individuals need to have lived in the UK for a sufficient period of time. You should normally have been resident in the United Kingdom for the last 3 years as the role requires Counter Terrorism Check (CTC). UK residency less than the outlined periods may not necessarily bar you from gaining national security vetting and applicants should contact the Vacancy Holder / Recruiting Manager listed in the advert for further advice.  

Person specification

Essential Criteria

Essential criteria
  • Degree in Bioinformatics or a related discipline such as Computer science, informatics or microbiology and/or relevant experience in computer science or health informatics
  • Application and adaptation of bioinformatics tools to analyse biological data using the UNIX command line
  • Experience in the analysis of large molecular datasets (incl. next-generation/ whole genome sequences)
  • Demonstrable experience in programming and script writing (eg. Python, bash)
  • Good time management skills, the ability to multitask and be able to work to deadlines and achieve milestones.
  • An understanding of and commitment to equality of opportunity and good working relationships.

Employer certification / accreditation badges

Purple SpaceApprenticeships logoNo smoking policyAge positiveImproving working livesMindful employer.  Being positive about mental health.Disability confident employerThe Employers Network for Equality & Inclusion (enei) is the UK's leading employer network covering all aspects of equality and inclusion issues in the workplace.Carer Confident -AccomplishedHappy to Talk Flexible Working

Documents to download

Apply online now

Further details / informal visits contact

Name
Gurkamal Bhambra
Job title
Resourcing
Email address
[email protected]
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