Job summary
- Main area
- Bioinformatician
- Grade
- Civil Service: Higher Executive Officer (HEO)
- Contract
- Fixed term: 11 months (FTC till 31/03/26)
- Hours
- Full time
- Part time
- Job share
- Flexible working
- Job ref
- 919-GB-301386-EXT
- Employer
- UK Health Security Agency
- Employer type
- Public (Non NHS)
- Site
- Colindale
- Town
- Colindale
- Salary
- £36,187 - £43,552 Per annum, Pro rata
- Salary period
- Yearly
- Closing
- 15/05/2025 23:59
Employer heading

Bioinformatician
Civil Service: Higher Executive Officer (HEO)
Job overview
The Gastrointestinal Bacteria Reference Unit (GBRU) undertakes surveillance, advises on outbreak investigation and on any public health risk. With the increasing development of genomics including the generation of sequence data from whole genomic sequencing, this role is key to supporting the Unit with necessary bioinformatic expertise and advice regarding appropriate analysis tools, equipment and procedures for the analysis of complex scientific information for the development and support of reference services
You will support development of bioinformatics and public health informatics for GBRU:
- Compile, in appropriate databases and formats, complex data arising from whole-genome sequencing (WGS) from a range of gastrointestinal bacterial pathogens.
- Support the development bioinformatics tools and pipelines suitable for analysis and comparison of the genome sequences generated.
- Undertake analyses on data arising from WGS for reference service delivery, including outbreak analysis, bacterial discrimination, and service development projects, and to assist in the timely generation of meaningful reports to customers.
- Support preparation of reports, posters and publications arising from data at national and international meetings
Main duties of the job
- Contribute to day-to-day running and maintenance of the software and computer systems delivering existing Whole Genome Sequencing (WGS) pipelines.
- Work with bioinformaticians at UKHSA on efficient bioinformatics pipelines suitable for analysis and comparative genomics of bacterial genome sequences, within GBRU’s remit.
- Compile data arising from priority projects/routine data to characterize bacterial pathogens
- Assist to provide a flexible laboratory response to emergency public health needs including outbreaks of gastrointestinal disease and general investigations of illness as appropriate
- Assist with evaluation and implementation of new techniques / methods to the unit that enhance effectiveness of the laboratory work with genomic platforms
- Undertake analysis of data arising from GBRU genome sequencing projects, including temporal and geographical cluster analysis, characterization of clones, resistance / virulence array data, full genome or resistance plasmid sequencing
- Train others in the use of tools developed
- Write and update working instruction and SOPs
- Prepare reports, posters and publications arising from the data analysis and present findings at internal and/or external meetings
- Comply with safety and quality protocols and procedures at all times.
For a full list of the main duties and responsibilities of the role, please refer to the attached Job Description.
Working for our organisation
We pride ourselves as being an employer of choice, where Everyone Matters promoting equality of opportunity to actively encourage applications from everyone, including groups currently underrepresented in our workforce. UKHSA ethos is to be an inclusive organisation for all our staff and stakeholders. To create, nurture and sustain an inclusive culture, where differences drive innovative solutions to meet the needs of our workforce and wider communities. We do this through celebrating and protecting differences by removing barriers and promoting equity and equality of opportunity for all. Please visit our careers site for more information https://gov.uk/ukhsa/careers
Detailed job description and main responsibilities
Essential role criteria:
- Degree in Bioinformatics or a related discipline such as Computer science, informatics or microbiology and/or relevant experience in computer science or health informatics
- Application and adaptation of bioinformatics tools to analyse biological data using the UNIX command line
- Experience in the analysis of large molecular datasets (incl. next-generation/ whole genome sequences)
- Demonstrable experience in programming and script writing (eg. Python, bash)
- Good time management skills, the ability to multitask and be able to work to deadlines and achieve milestones.
- An understanding of and commitment to equality of opportunity and good working relationships.
Desirable role criteria:
- An understanding of the principals of DNA sequence analysis and phylogenetics
- Knowledge of molecular microbiology and molecular epidemiology
- Experience in working with complex datasets and within challenging environments
- Knowledge of Bacterial Pathogens
- Understanding of the public sector (working with various government bodies)
- Database management (PostgreSQL, SQL queries)
- Public speaking at national or international meetings
- Problem solving skills and ability to respond to sudden unexpected demands
Selection Process Details:
This vacancy will be assessed using a competency-based framework which will assess your qualifications, knowledge and experience and / or skills and abilities outlined in the essential criteria.
Stage 1: Application & Sift - Competency-based assessment
You will be required to complete an application form. You will be assessed on the listed (6) essential criteria, and this will be in the form of a:
- Application form (‘Employer/ Activity history’ section on the application)
- 1250 word Statement of Suitability.
This should outline how your skills, experience, and knowledge, provide evidence of your suitability for the role, with reference to the essential criteria.
The Application form and Statement of Suitability will be marked together.
Longlisting:
In the event of a large number of applications we will longlist into 3 piles of:
- Meets all essential criteria
- Meets some essential criteria
- Meets no essential criteria
The following will be taken through to the next stage:
- Meets all essential criteria
Shortlisting:
In the event of a large number of applications we will shortlist on the following:
- Degree in Bioinformatics or a related discipline
Desirable criteria may be used in the event of a large number of applications / large amount of successful candidates
If you are successful at this stage, you will progress to interview & assessment
Please do not exceed 1250 words. We will not consider any words over and above this number.
Feedback will not be provided at this stage.
Please note you will not be able to upload your CV. You must complete the application form in as much detail as possible. Please do not email us your CV.
Stage 2: Interview (competency based)
You will be invited to a (single) face to face interview at Colindale. If face to face interviews are planned, in exceptional circumstances, we may be able to offer a remote interview.
Knowledge, experience, skills & abilities will be tested at interview
There will be a 5-10 minute Presentation. Further details will be provided at this stage.
Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.
Eligibility Criteria - External
Open to all external applicants (anyone) from outside the Civil Service (including by definition internal applicants).
Location
This role is being offered as hybrid working based at our Core HQ in Colindale. We offer great flexible working opportunities at UKHSA and operate using a hybrid working model where business needs allow. This provides us with greater flexibility about how and where we work, to get the best from our workforce. As a hybrid worker, you will be expected to spend a minimum of 60% of your contractual working hours (approximately 3 days a week pro rata, (averaged over a month). Our core HQ offices are modern and newly refurbished with excellent city centre transport link and benefit from benefit from co-location with other government departments such as the Department for Health and Social Care (DHSC).
Security Clearance Level Requirement
Successful candidates must pass a disclosure and barring security check.
Successful candidates must meet the security requirements before they can be appointed. The level of security needed is Counter-terrorist Check.
For meaningful National Security Vetting checks to be carried out individuals need to have lived in the UK for a sufficient period of time. You should normally have been resident in the United Kingdom for the last 3 years as the role requires Counter Terrorism Check (CTC). UK residency less than the outlined periods may not necessarily bar you from gaining national security vetting and applicants should contact the Vacancy Holder / Recruiting Manager listed in the advert for further advice.
Person specification
Essential Criteria
Essential criteria
- Degree in Bioinformatics or a related discipline such as Computer science, informatics or microbiology and/or relevant experience in computer science or health informatics
- Application and adaptation of bioinformatics tools to analyse biological data using the UNIX command line
- Experience in the analysis of large molecular datasets (incl. next-generation/ whole genome sequences)
- Demonstrable experience in programming and script writing (eg. Python, bash)
- Good time management skills, the ability to multitask and be able to work to deadlines and achieve milestones.
- An understanding of and commitment to equality of opportunity and good working relationships.
Documents to download
Further details / informal visits contact
- Name
- Gurkamal Bhambra
- Job title
- Resourcing
- Email address
- [email protected]
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