Job summary
- Main area
- Science
- Grade
- NHS AfC: Band 8c
- Contract
- Permanent
- Hours
- Full time
- Part time
- Job share
- Flexible working
- Job ref
- 919-301753-EXT
- Employer
- UK Health Security Agency
- Employer type
- Public (Non NHS)
- Site
- Colindale
- Town
- Colindale, London
- Salary
- £76,965 - £88,682 per annum, pro rata. Plus, Outer HCAS. Up to 15% of basic salary PA PR
- Salary period
- Yearly
- Closing
- 17/12/2025 23:59
Employer heading
Unit Head of Colindale Sequencing Laboratory (CSL)
NHS AfC: Band 8c
Job overview
The Colindale Sequencing Laboratory (CSL) provides a variety of nucleic acid sequencing services using Next Generation Sequencing (NGS) and Sanger technology to sequence genomic DNA, PCR amplicons, or short DNA fragments, as well as providing DNA-based fragment analysis to size fluorescently labelled PCR products. For Sanger sequencing and fragment analysis, the unit receives nucleic acid, plasmids and PCR products from UKHSA and external customers. CSL also offers various levels of NGS for genomic DNA (usually bacterial DNA extracts) and PCR amplicons (usually generated from viral samples) to service users. NGS is currently performed using Illumina or Oxford Nanopore Technology (ONT) on the NextSeq, MiSeq or GridION. Sequence and fragment analysis data are checked by CSL staff against internal standards and quality scores before electronically notifying and reporting the results to our customers, who analyse their own data.
CSL has a strong service delivery focus and commitment to continuously improving methods for rapid and high throughput genomics to enhance its function.
The Unit Head of the CSL is responsible for leading and managing the routine provision, delivery and development of genomic services for customers of CSL, and acts as the senior specialist for NGS and Sanger services. The post holder will be accountable for scientists within the unit, providing leadership and oversight for the day-to-today running and development of the NGS and Sanger services.
Main duties of the job
- Responsible for provision of expert scientific leadership, the strategic development and operational service delivery of the CSL.
- To advise Public Health Microbiology (PHM) Laboratories and UKHSA on best practice in laboratory sequencing.
- To manage the provision of an efficient, effective and timely service, ensuring maximum productivity within allocated resources/budgets and within agreed performance standards.
- To ensure the CSL offers genomic services under a Quality Management System in accordance with UKHSA policies, and Quality standards set by external accreditation bodies (e.g. UKAS).
- To be accountable for Health and Safety within the CSL.
- To ensure that the CSL delivers and develops services and provides expert advice for wider public health delivery, and also provides national and international specialist services and advice to customers.
- Provide leadership to ensure services contribute to the national development of genomics-based PHM delivery.
- Contribute to test development and validation.
- Review platform use and manage implementation of new equipment to support service delivery improvement.
- To maintain and further develop the national and international reputation of the CSL through development of strategic academic, public sector and other partnerships including funding application, participation, design, implementation and overall management of appropriate R&D projects.
Working for our organisation
We pride ourselves as being an employer of choice, where Everyone Matters promoting equality of opportunity to actively encourage applications from everyone, including groups currently underrepresented in our workforce. UKHSA ethos is to be an inclusive organisation for all our staff and stakeholders. To create, nurture and sustain an inclusive culture, where differences drive innovative solutions to meet the needs of our workforce and wider communities. We do this through celebrating and protecting differences by removing barriers and promoting equity and equality of opportunity for all. Please visit our careers site for more information https://gov.uk/ukhsa/careers
Detailed job description and main responsibilities
- In partnership with PHM Laboratories staff, develop strong integration between nucleic acid extraction and upstream sample processing.
- Maintain strong linkages with the processing and analysis of sequence data.
Detailed job description and main responsibilities
- To be responsible for the provision of expert advice and CSL services for clinically significant organisms, including the provision of interpretation of data for laboratory reports with expert comment and advice to Consultant Medical Microbiologists, Consultants in Health Protection, Senior Officers of the Department of Health and Social Care and other Government bodies and international Institutes.
- Work collaboratively with UKHSA and NHS laboratories and other Government bodies, Academic and international Institutes and provide support, leadership and strategy for the implementation and development of molecular technologies for Clinical PHM (supporting UKHSA, NHS and Academic and other institutes).
- On behalf of UKHSA provide expert scientific, professional and managerial inputs for the activities of Working Groups and Specialist committees in pathogen laboratory sequencing.
- To be responsible for the management, health and safety and training of CSL staff, visitors, trainees and PhD students.
- To maintain an awareness of Health and Safety and comply with current site requirement and ensure that relevant legislations and policies are implemented within CSL and ensure that it is compliant with statutory Health and Safety Regulations, including COSHH, together with the appropriate accreditation systems and that staff have appropriate registration and maintain participation with Continued Professional Development Schemes.
- To manage the CSL budget, including budget control, expenditure projections, equipment priorities, external funding and income generation activities.
- Manage the quality, performance and verification of the accredited CSL laboratory services ensuring compliance with UKAS standards.
- To assist in the operation of PHM Laboratories by membership of PHM Management Groups.
- To represent CSL and PHM laboratories at internal/external, local, national & international meetings and committees.
- To lead working groups and discussion on the strategic planning and implementation of UKHSA sequencing services.
- To contribute, manage and provide expertise and leadership to CSL business management including negotiation with customers, reviewing efficiency and Unit performance and pursuing business opportunities within UKHSA and with external customers.
- To be an on-call expert in laboratory sequencing of bio-threat agents.
This is not an exhaustive list.
Essential criteria
- Degree (BSc / MSc) in a biological science, molecular biology or bioinformatics.
- PhD in molecular microbiological subject or equivalent experience in relevant laboratory sciences
- Relevant professional qualification i.e., registration with the Health and Care Professions Council (HCPC) as Clinical Scientist or Biomedical Scientist
- Expertise in the areas covered by the unit and experience in running NGS Platforms and Applied Biosystems sequencing
- Proven and extensive experience of supervision and leadership
- Knowledge of automated liquid handling
- Experience, knowledge and understanding of Quality Assurance Principles and Procedures
- Experience, knowledge and understanding of laboratory safety requirements and procedures
- Experience in training staff and competency assessment
- Knowledge of clinical microbiology, including bacteriology and virology.
- Data analysis and data presentation skills: Presenting evaluation information to meetings/groups where highly qualified experts debate the work the post holder has prepared
- Skills for communication on complex information and administrative matters, requiring developed interpersonal and oral/ written communication skills
- Able to communicate effectively with all grades of staff both internal and external to the UKHSA
- Problem solving skills and ability to respond to sudden unexpected demands
- Advanced keyboard skills, use of a range of software
- Ability to work on own initiative and organise own workload with minimal supervision working to tight and often changing timescales
- An understanding of and commitment to equality of opportunity and good working relationships, both in terms of day-to-day working practices, but also in relation to management systems
Desirable criteria:
- Relevant business or management training to certificate level
- Experience and knowledge of project principles
- Evidenced management experience of at least five years for scientific, technical and student staff.
- R&D project management and team building experience
- Strong R&D publication record and presenting at national and international audience
- Ability to attract external and internal grant funding
- Excellent time management skills with the ability to re-prioritise
Selection Process Details:
This vacancy will be assessed using a competency-based framework which will assess your qualifications, knowledge and experience and / or skills and abilities outlined in the essential criteria.
Stage 1: Application & Sift
You will be required to complete an application form. You will be assessed on the listed 17 essential criteria, and this will be in the form of a:
- Application form (‘Employer/ Activity history’ section on the application)
- Up to 1,200 supporting statement
This should outline how your skills, experience, and knowledge, provide evidence of your suitability for the role, with reference to the essential criteria.
The Application form and supporting statement will be marked together.
Please note you will not be able to upload your CV. You must complete the application form in as much detail as possible. Please do not email us your CV.
Longlisting:
In the event of a large number of applications we will longlist into 3 piles of:
- Meets all essential criteria
- Meets some essential criteria
- Meets no essential criteria
The following will be taken through to the next stage:
- Meets all essential criteria
- Meets some essential criteria
Shortlisting:
In the event of a large number of applications we will shortlist on the following:
- Degree (BSc / MSc) in a biological science, molecular biology or bioinformatics.
- PhD in molecular microbiological subject or equivalent experience in relevant laboratory sciences
- Relevant professional qualification i.e., registration with the Health and Care Professions Council (HCPC) as Clinical Scientist or Biomedical Scientist
- Expertise in the areas covered by the unit and experience in running NGS Platforms and Applied Biosystems sequencing
- Proven and extensive experience of supervision and leadership
Desirable criteria may be used in the event of a large number of applications / large amount of successful candidates.
If you are successful at this stage, you will progress to interview & assessment.
Please do not exceed 1,200 words. We will not consider any words over and above this number.
Feedback will not be provided at this stage.
Stage 2: Interview (competency based)
You will be invited to a (single) face to face interview at Colindale. In exceptional circumstances, we may be able to offer a remote interview via teams.
Knowledge, experience, skills & abilities will be tested at interview
You will be asked to prepare and present a 10-minute presentation at the start of your interview. The presentation will be designed to allow the candidates to demonstrate their knowledge of and experience in leading and delivering a Next Generation Sequencing service. Full details will be provided at interview stage.
Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.
Location
This role is being offered as hybrid working based at our Scientific Campus in Colindale.
We offer great flexible working opportunities at UKHSA and operate using a hybrid working model where business needs allow. This provides us with greater flexibility about how and where we work, to get the best from our workforce. As a hybrid worker, you will be expected to spend a minimum of 60% of your contractual working hours (approximately 3 days a week pro rata, (averaged over a month).
If based at one of our scientific campuses, you will be required to have a minimum of a Counter Terrorism Check security vetting check as a minimum. For meaningful National Security Vetting checks to be carried out individuals need to have lived in the UK for a sufficient period of time. You should normally have been resident in the United Kingdom for the last 3 years as the role requires Counter Terrorism Check (CTC) clearance. In exceptional circumstances UK residency less than the outlined periods may not necessarily bar you from gaining national security vetting and applicants should contact the Vacancy Holder/Recruiting Manager listed in the advert for further advice.
Security Clearance Level Requirement
Successful candidates must pass a disclosure and barring security check.
Successful candidates must meet the security requirements before they can be appointed. The level of security needed is Counter-terrorist Check.
Eligibility Criteria – External
Open to all external applicants (anyone) from outside the Civil Service (including internal applicants).
Salary Information
If you are successful at interview, and are moving from another government department, NHS, or Local Authority, the relevant starting salary principles for level transfers or promotions will apply. Otherwise, roles are offered at the pay scale minimum for the grade, but in exceptional circumstances there may be flexibility if you are able to demonstrate you are already in receipt of an existing, higher salary. Pay increases are through the relevant annual pay award for the role and terms.
Person specification
Application form and supporting statement
Essential criteria
- Application form and supporting statement
Essential Criteria
Essential criteria
- Questions on experience, knowledge and skills
Essential Criteria
Essential criteria
- Presentation
Applicant requirements
You must have appropriate UK professional registration.
Documents to download
Further details / informal visits contact
- Name
- Gurkamal Bhambra
- Job title
- Resourcing
- Email address
- [email protected]
- Additional information
For information regarding the role please contact [email protected]
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