Job summary
- Main area
- Renal Transplant
- Grade
- Junior Clinical Fellow
- Contract
- 1 year (Fixed term 12 months)
- Hours
- 40 hours per week (full time)
- Job ref
- 391-RFL-7683459
- Employer
- Royal Free London NHS Foundation Trust
- Employer type
- NHS
- Site
- Royal Free Hospital
- Town
- Hampstead
- Salary
- £52,656 - £65,048 per annum plus London Weighting
- Salary period
- Yearly
- Closing
- 02/01/2026 23:59
Employer heading
Junior Clinical Research Fellow in Renal Transplantation
Junior Clinical Fellow
Our trust has over 17,000 staff serving 2 million patients every year. It comprises Barnet Hospital, Chase Farm Hospital, the Royal Free Hospital, North Middlesex University Hospital and more than 30 services in the community. This larger scale organisation provides an unprecedented opportunity for us to continue our pioneering work, particularly in finding ways to deliver even better care to our patients.
Our mission is to deliver world class care and expertise in our clinical services, underpinned by world class teaching and research and we will continue to measure our progress against our five governing objectives: excellent outcomes, excellent patient and staff experience, excellent value for taxpayers’ money, being safe and meeting our external duties, and building a strong organisation.
Everyone is welcome at Royal Free London NHS Foundation Trust. We're proud of our diversity and we continue to undertake new initiatives to advance equality for LGBT+, BME, gender equality, staff carers and people with disabilities and lived experiences to promote good relations and understanding between our staff.
Click here to view our video Welcome to the Royal Free
Job overview
Applications are invited for a Clinical Research Fellow to support the conduct of the PROSPECT Study – Physiological Response to Once-Daily Tacrolimus (LCP-T) – at the Royal Free Hospital.
This is a fully funded research post delivered within the Renal, Nephrology and Renal Transplant Services, working under the supervision of the Principal Investigator, Dr Rhys Evans. The post-holder will support delivery of Phase 1 and Phase 2 research activity in accordance with the study protocol, NIHR and GCP standards.
The study is supported through research funding provided by Chiesi Ltd to the Royal Free London NHS Foundation Trust. This funding supports research personnel, materials and delivery of study milestones.
This post is exclusively research-focused with no clinical service commitment.
Main duties of the job
The PROSPECT Study (Physiological Response to Once-Daily Tacrolimus [LCP-T]) is a multi-phase, observational research programme evaluating pharmacokinetics, pharmacodynamics, and immunological responses to once-daily tacrolimus in kidney and liver transplant recipients at the Royal Free Hospital.
Phase 1 includes large-scale metabolomic and biochemical analysis in approximately 600 transplant recipients to characterise drug exposure profiles and identify predictors of variability.
Phase 2 involves detailed sub-study monitoring of 40 transplant patients (20 kidney, 10 liver, 10 control) to explore longitudinal changes in drug exposure, biomarkers and immunological response. The post-holder will assist with recruitment, participant follow-up, data acquisition and sample handling.
This role provides experience in transplant research, specialist assay methodologies and regulated delivery of commercial-supported studies. The PROSPECT Study (Physiological Response to Once-Daily Tacrolimus [LCP-T]) is a multi-phase, observational research programme evaluating pharmacokinetics, pharmacodynamics, and immunological responses to once-daily tacrolimus in kidney and liver transplant recipients at the Royal Free Hospital.
Working for our organisation
The Royal Free London NHS Foundation Trust is one of the UK’s biggest and most innovative trusts. Across three main hospitals, our dedicated army of staff care for over 1.6million patients, treat more than 200,000 in A&E, deliver over 8,000 babies and carry out more than 17million tests.
Our size, scale and influence offer you unrivalled career opportunities and a forward-thinking approach to working that works around your lifestyle. From flexible hours and generous benefits, to next level training, we make it easier to take your career to the top
For more information please follow link https://www.royalfreelondonjobs.co.uk/
Detailed job description and main responsibilities
Please see attached job description for more information about this role and working at Royal Free London NHS Foundation Trust.
Person specification
Royal Free World Class Values
Essential criteria
- Demonstrable ability to meet the Trust Values
Education & professional Qualifications
Essential criteria
- MBBS or equivalent
- Full GMC registration with license to practice
- Good Clinical Practice Training Certificate
Desirable criteria
- Membership of relevant Royal College or oversees equivalent
Experience
Essential criteria
- Work in a clinical trials or research environment
- Experience in data collection, management, analysis and presentation
Desirable criteria
- Relevant experience in medical specialities
- Experience in transplant or immunology field
- Involvement in the clinical audit process and an understanding of the aims thereof
Skills and aptitudes
Essential criteria
- Excellent communication skills/verbal and written
- Ability to take on tasks and responsibilities in a multi-professional team and to be able to work effectively and sensitively within it
Desirable criteria
- Proven ability in relevant subject areas
Personal Qualities and atributes
Essential criteria
- Ability to organise and prioritise workload
- High ethical and professional standards in research, education and clinical practice
Others
Essential criteria
- Knowledge of the Clinical Governance framework of the NHS (including Research Governance). Ability to act within these parameters
- GMC registration or eligibility for GMC registration
Applicant requirements
You must have appropriate UK professional registration.
This post is subject to the Rehabilitation of Offenders Act 1974 (Exceptions) Order 1975 (Amendment) (England and Wales) Order 2020 and it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service.
Application numbers
Documents to download
Further details / informal visits contact
- Name
- Prof Rhys Evans
- Job title
- Clinical Lead for Kidney Transplantation
- Email address
- [email protected]
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