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Job summary

Main area
Onc & Haem Clinical Trials (OHCT)
Grade
Band 5
Contract
Permanent
Hours
Full time - 37.5 hours per week
Job ref
196-RD343
Employer
Guy's and St Thomas' NHS Foundation Trust
Employer type
NHS
Site
Guy's Hospital Site
Town
London
Salary
£37,259 - £45,356 p.a inc. of HCA
Salary period
Yearly
Closing
10/08/2025 23:59

Employer heading

Guy's and St Thomas' NHS Foundation Trust logo

Clinical Research Nurse

Band 5

Guy’s and St Thomas’ is among the UK’s busiest and most successful NHS foundation trusts. We provide a full range of hospital and community services for people in south London and as well as specialist care for patients from further afield including cancer, renal, orthopaedic, respiratory and cardiovascular services.

Guy’s is home to the largest dental school in Europe and a £160 million Cancer Centre opened in 2016. As part of our commitment to provide care closer to home, in 2017 we also opened a cancer centre and a kidney treatment centre at Queen Mary’s Hospital in Sidcup. St Thomas’ has one of the largest critical care units in the UK and one of the busiest emergency departments in London. It is also home to Evelina London Children’s Hospital.

Evelina London cares for local children in Lambeth and Southwark and provides specialist services across south east England including cardiac, renal and critical care services. We lead a number of specialist service networks aiming to ensure children are treated locally where possible, but have access to specialist expertise when they need it. Our community services include health visiting, school nursing and support for families of children with long-term conditions. 

Our adult community services teams deliver care at the heart of the local communities we serve, working in partnership with GPs, local authorities and other healthcare and voluntary sector organisations. Working with our partners in Lambeth and Southwark, we are focusing on new ways of working to improve care for local patients.

In February 2021 the Royal Brompton and Harefield joined Guy’s and St Thomas’ NHS Foundation Trust, bringing together world-leading expertise in the care and research of heart and lung disease. Our merger provides a once in a generation opportunity to build a lasting, world-renowned heart and lung centre, providing the highest quality care for patients and conducting world-leading research.

We have a reputation for clinical excellence and high quality teaching and research. We are part of King’s Health Partners, one of eight accredited UK academic health sciences centres. In partnership with King’s College London we have dedicated clinical research facilities including an MHRA accredited Phase I clinical trials unit.

Patients are at the heart of everything we do and we pride ourselves on ensuring the best possible patient experience as well as safe, high quality care. We are proud to have one of the lowest mortality rates in the NHS. Following a comprehensive Care Quality Commission (CQC) inspection in 2019 we maintained our overall rating of ‘good’. Our adult community services achieved a rating of ‘outstanding’.

The commitment of our 23,500 staff is key to our success. We are one of the largest local employers and we aim to develop and support all our staff so they are able to deliver high quality, safe and efficient care. The 2019 NHS staff survey results show that we have one of the most engaged and motivated workforces in the NHS. We know this has a positive impact on the care provided to our patients.

We have one of the most ambitious capital investment programmes anywhere in the NHS.



Job overview

The Oncology and Haematology Clinical Trials (OHCT) team manages clinical trials within Guy’s & St Thomas’ NHS Foundation Trust (GSTFT). The team has an excellent reputation nationally and globally in providing excellent patient care and putting their safety at the core of our practice. GSTFT value research, the work we do contributes to finding new cancer treatments and improving patient’s quality of life. 

  • As a band 5 you will have a fantastic opportunity for training and career development within the specialty of GI or Skin research  nursing. You will be working closely with experienced research nurses, doctors and other members of the multi-disciplinary team in caring for Oncology patients within clinical trials.

    The role will include identifying patients suitable for clinical trials and support them and their families throughout their participation in clinical trials.

You will require:

  • Substantial clinical experience
  • Accuracy and attention to detail
  • Ability to work autonomously and have good skills in time management
  • Excellent communication and interpersonal skills
  • Can balance clinical work and non-clinical work as per research requirements

Main duties of the job

The post holder will be expected to manage a caseload of patients and have the duty of care in supporting them and their families throughout their participation in clinical trials.  The role will include identifying suitable patients for clinical trials and work autonomously within professional practice guidelines and within Research Governance Framework.

The post holder will also provide a full administrative service to the tumour specific research team. They will have a pivotal role in the running of national and international phase I, II, and III oncology and clinical trials.

Responsibilities will include the creation and maintenance of site files, formulating worksheets, the collection and transcribing of trial data, completing case report forms and the maintenance of a database of trial activity. 

Working for our organisation

As part of Kings Health Partners, the Oncology and Haematology Clinical Trials (OHCT) team is made up of fifty plus staff members consisting of Research Nurses, Clinical Research Practitioners,  and the Safety & Support Team at Guys’ and St Thomas’ NHS Foundation Trust. We work closely with the oncology and haematology medical teams to recruit patients to our trials and to ensure patients are monitored closely throughout. We have a large portfolio of Phase II and III trials; which are split into teams for specific tumour groups.

We also have a team dedicated to early phase trials and run weekly early phase clinics in the Clinical Research Facility. We attract commercial and non-commercial trials, ranging from interventional drug or radiotherapy trials to observational studies.

Our mission statement is ‘Improving treatment choice, clinical care and outcomes for cancer patients through innovation, dedication and excellence in clinical trials’.

Detailed job description and main responsibilities

Clinical research

Work autonomously to manage a caseload of patients acting as a professional
in ensuring a duty of care to the patient and their families

Identify patients suitable for entry into clinical trials by attending clinics
(screening notes/consultant referral) and Multidisciplinary Team (MDT)
meetings

Participate in the informed consent process acting as a resource and support to patients and their families

Co ordinate the research patient pathway from screening through to trial
closure

Advise and train the local nursing team who administer trial drugs, be aware of and report any side effects as outlined in the protocol

Maintain adequate patients’ records and ensure all relevant information is documented in the patient’s medical and nursing notes

Keep up to date with current practices for cannulation, phlebotomy, care of patients with Central Venous Access lines and handling and administration of cytotoxic chemotherapy

Act as a role model for excellence in oncology based research

Lead on a portfolio of trials and coordinate patient participation, paying
particular attention to accurate data collection and transfer and version control of essential documentation 

Liaise with the clinical team to organise and ensure that trial specific
investigations are undertaken according to the protocol and obtain the results

Liaise with trial pharmacy to co-ordinate the availability and dispensing of trial drugs if required

Process blood samples according to the trial-specific lab manual and organise the storage and shipment of protocol specific samples

Work in accordance with all regulatory requirements including: local Standard Operating Procedures (SOPs), Good Clinical Practice, (GCP) European Directives,  Medicines for Human Use (Clinical Trials), Regulations  Research Governance Framework for Health and Social Care, Human Tissue Act

Lead on stock control and ordering of consumables

Organisational

Complete case report forms in a precise and timely manner, ensuring that all the relevant clinical data in the patient’s medical notes and trial file is transcribed accurately.

Prepare the relevant essential documentation required when setting up a trial.
Assist in completing submissions to Research & Development Department.

Create and maintain the file of current protocols and patient information sheets, ensuring version control. Be responsible for the maintenance of the Investigator Site Files.

Assist in the creation and maintenance of good office systems for the
smooth running of the service.

Deal with data queries in a timely and efficient manner.

Organise and prepare documentation for audit and monitoring visits.

Provide information to allow invoices to be raised for payment where appropriate.
Arrange, attend and record minutes for research and other relevant departmental meeting.

Actively seek to develop the role to take account of changing requirements of the service. Portfolio Management and Development

Liaise with Clinical Trial Set Up staff to help assist in the set-up of trials on site

Process amendments and disseminate information to relevant departments

Assist in the provision of information to allow for invoices to be raised for payments where appropriate

Build strong professional relationships with other departments in order to promote a good working environment

To report clinical incidents as per Trust policy and local SOP

Maintain a dialogue of progress with the Research Team Leader

Attend weekly team handover meetings

Provide cover when necessary for annual leave, study leave, sick leave.

Further information on the role and its requirements can be found in the attached job description and person specification documentation

Person specification

Experience

Essential criteria
  • At least one year experience in relevant acute setting
  • Excellent computer literacy (email, Microsoft Word, Excel, databases)
  • Knowledge of cancer pathways
Desirable criteria
  • Experience in research methodologies

Skills and Abilities

Essential criteria
  • Ability to work autonomously and as a member of a small team, as well as part of the wider multidisciplinary team
  • Ability to work across boundaries, integrating with multidisciplinary staff in relation to research trials.
  • Excellent communication and interpersonal skills
  • Accuracy and attention to detail in data collection
Desirable criteria
  • Word processing, report writing and presentation skills.

Education and Qualifications

Essential criteria
  • NMC Level One Registration – RN Adult
  • Evidence of continuous personal, professional and academic development
Desirable criteria
  • Relevant post registration qualification in cancer or research nursing
  • Awareness in changing trends within health and cancer care
  • Basic knowledge of recent NHS legislation and recommendations in the field of cancer and palliative care

Employer certification / accreditation badges

Timewise helps businesses to attract and develop the best talent through flexible working.Care quality commission - GoodDisability confident employer

Applicant requirements

You must have appropriate UK professional registration.

This post is subject to the Rehabilitation of Offenders Act 1974 (Exceptions) Order 1975 (Amendment) (England and Wales) Order 2020 and it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service.

Documents to download

Apply online now

Further details / informal visits contact

Name
Ellie McDowall
Job title
GI Research Team Lead
Email address
[email protected]
Additional information

Rumana Parvin

Skin Research Team Lead

[email protected]

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